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Tell your doctor about any illness or infection you have had within the past several weeks. Hydrocortisone is a steroid medicine that is used in the treatment of many different conditions, including allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, multiple sclerosis, or lung disorders. Hydrocortisone is also used to replace steroids in people with adrenal insufficiency decreased production of natural steroids by the adrenal glands.

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Large controlled studies on sex differences in the mineral corticoid effect of systemic hydrocortisone are lacking. A large meta-analysis have shown that high daily doses of oral glucocorticoids increase the risk of bone fractures to a similar degree in men and women, regardless of age and underlying disease. However, another large population-based study found a higher risk of fracture in women than men exposed to oral corticosteroids.

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Hydrocortisone belongs to a class of medicines known as corticosteroids more commonly called steroids. If you need any medical treatment, make sure the person treating you knows that you are taking hydrocortisone. This is because your dose may need to be increased for a short while.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. The purpose of this study is to use brain imaging technology to examine the effect of the hormone hydrocortisone on the brain's response to various facial expressions. Glucocorticoids can influence emotional behavior and cognition; when given long-term, the hormones may lead to mania or depression.

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The adrenal gland is divided into the adrenal medulla, which produces catecholamines such as epinephrine and norepinephrine, and the adrenal cortex, which produces cortical steroids such as cortisol, aldosterone, and androgens, all of which are needed to maintain homeostasis in the body. The adrenal cortex is further subdivided into 3 regions: the zona glomerulosa, which is responsible for producing mineralocorticoids eg, aldosterone ; the zona fasciculata, which secretes glucocorticoids eg, cortisol ; and the zona reticularis, which releases androgens eg, testosterone. The levels of these cortical steroids are regulated through the hypothalamuspituitary-adrenal HPA axis Figure.

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Drug information provided by: IBM Micromedex. Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

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Study record managers: refer to the Data Element Definitions if submitting registration or results information. The study will be conducted in two parts Part 1 and 2 which will not be performed sequentially. In Part 1, 24 subjects will be dosed in a fasted condition and in Part 2, 24 subjects will be dosed in a fed condition.

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Medically reviewed by Drugs. Last updated on Feb 5, Applies to hydrocortisone : oral tablet. Along with its needed effects, hydrocortisone may cause some unwanted effects.

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Primary hypoadrenalism; adrenal failure ; addison disease; addison syndrome; adrenal insufficiency; hypoadrenalism. The adrenal glands are triangular in shape, roughly up to three inches 7. The outer part of the adrenal gland called the cortex makes three separate types of hormone:.

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The main glucocorticoid secreted by the adrenal cortex. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions. A governmentally-recognized ID which uniquely identifies the product within its regulatory market.

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